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  4. L-Lysine α-oxidase

L-Lysine α-oxidase  (Synonyms: L-赖氨酸α-氧化酶)

目录号: HY-P2965
产品使用指南

摩尔计算器

L-Lysine α-oxidase 是一种有效的抗癌剂。L-Lysine α-oxidase 也是一种 L-氨基酸氧化酶，使 L-赖氨酸脱氨基，产生 H2O2、氨和 α-酮-ε-氨基己酸。L-Lysine α-oxidase 具有细胞毒性和抗癌活性。

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L-Lysine α-oxidase Chemical Structure

L-Lysine α-oxidase Chemical Structure

CAS No. : 70132-14-8

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25 U ￥11550
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L-Lysine α-oxidase 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L-Lysine α-oxidase is a potent anticancer agent. L-Lysine α-oxidase also a L-amino acid oxidase, deaminates L-lysine with the yield of H2O2, ammonia, and α-keto-ε-aminocaproate. L-Lysine α-oxidase shows cytotoxicity and anticancer activity[1][2].

体外研究
(In Vitro)

L-Lysine α-oxidase 对 HT29、LS174T、MCF7、SKOV3、PC3、K562 细胞具有细胞毒性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

L-Lysine α-oxidase 相关抗体:
体内研究
(In Vivo)

L-Lysine α-oxidase (第 2 天为 150 U/kg，第 4、6、8 和 10 天为 75 U/kg；腹腔注射) 在人类肿瘤模型中显示出抗癌活性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 6-9 weeks, Female Balb/c nude mice (SKBR3, HCT116, Bro, SKOV3, Alex, T47D, LS174T tumor models)[2]
Dosage: 150 U/kg on day 2 and 75 U/kg on days 4, 6, 8, and 10
Administration: I.p.; 10 U/ml saline solution
Result: Caused inhibition of tumor growth with maximal T/C of 49, 12, 51, 35, 54,36, 37% for SKBR3, HCT116, Bro, SKOV3, Alex, T47D, LS174T tumor models, respectively.
CAS 号
中文名称

L-赖氨酸α-氧化酶
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

L-Lysine α-oxidase 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Lysine α-oxidase70132-14-8L-赖氨酸α-氧化酶OtherscytotoxicityanticancerHCT 116LS174TT47D cellsInhibitorinhibitorinhibit

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