2. Anti-infection
  3. Bacterial
  4. L-NBDNJ

L-NBDNJ 是一种糖模拟物，是一种抗毒力剂。L-NBDNJ 会干扰调节宿主细胞骨架组装和组织的蛋白质的表达。L-NBDNJ 在囊性纤维化 (CF) 肺病感染模型中具有抗炎和抗感染作用。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

L-NBDNJ Chemical Structure

L-NBDNJ Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

L-NBDNJ 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L-NBDNJ, a glycomimetic, is an antivirulence agent. L-NBDNJ interferes with the expression of proteins regulating cytoskeleton assembly and organization of the host cell. L-NBDNJ has anti-inflammatory and anti-infective effects in models of cystic fibrosis (CF) lung disease infection[1].

体外研究
(In Vitro)

L-NBDNJ 是一种糖模拟物，是一种抗毒力剂。L-NBDNJ 会干扰调节宿主细胞骨架组装和组织的蛋白质的表达。L-NBDNJ 必须 干扰参与宿主细胞骨架组装和组织的代谢途径，下调参与宿主反应的铜绿假单胞菌的主要毒力因子，并影响病原体对人体细胞的粘附[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

L-NBDNJ 相关抗体:
体内研究
(In Vivo)

L-NBDNJ（10-100 mg/kg；口服管饲；每日；持续 6 天）在小鼠中表现出抗炎和抗感染作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: C57Bl/6NCr mice infected by P. aeruginosa MDR-RP73[1]
Dosage: 10 and 100 mg/kg
Administration: Oral gavage; daily; for 6 days (starting 24 h before infection)
Result: A significant and substantial decrease in bacteria recovered from the airways of mice observed[1].
Showed a moderate reduction of some chemokines and cytokines activated by infection[1].
分子量

219.28

Formula

C10H21NO4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

L-NBDNJ 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-NBDNJBacterialanti-inflammatoryanti-infective effectscystic fibrosisantivirulence agentInhibitorinhibitorinhibit

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产品名称：
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目录号：
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