1. Neuronal Signaling
  2. Glucosylceramide Synthase (GCS)
  3. (−)-L-threo-PDMP hydrochloride

(−)-L-threo-PDMP hydrochloride 

目录号: HY-116392A
产品使用指南

(−)-L-threo-PDMP hydrochloride 是 (−)-L-threo-PDMP 的盐酸盐形式。L-threo-PDMP 是一种葡萄糖神经酰胺合成酶 (GCS) 抑制剂。L-threo-PDMP 刺激培养的主动脉平滑肌细胞的增殖,并增加 B16 黑色素瘤细胞中 LacCer 的水平。

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(−)-L-threo-PDMP hydrochloride Chemical Structure

(−)-L-threo-PDMP hydrochloride Chemical Structure

CAS No. : 161491-04-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(−)-L-threo-PDMP hydrochloride is the hydrochloride form of (−)-L-threo-PDMP. L-threo-PDMP is a glucosylceramide synthase (GCS) inhibitor. L-threo-PDMP stimulates the proliferation of cultured aortic smooth muscle cells, and that increases the level of LacCer in B16 melanoma cells[1][2].

分子量

427.02

Formula

C23H39ClN2O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
(−)-L-threo-PDMP hydrochloride
目录号:
HY-116392A
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