2. Apoptosis Protein Tyrosine Kinase/RTK
  3. c-Met/HGFR Apoptosis
  4. LAH-1

LAH-1 是一种具有口服活性和膜通透性的 c-Met 抑制剂 IC50 为 49 nM。LAH-1 具有抗癌活性，能诱导细胞凋亡 (apoptosis)、迁移和侵袭。

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LAH-1 Chemical Structure

LAH-1 Chemical Structure

CAS No. : 3018150-68-7

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LAH-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LAH-1 is a c-Met inhibitor with oral activity and membrane permeability with an IC50 of 49 nM. LAH-1 has anticancer activity and can induce apoptosis, migration, and invasion[1].

IC50 & Target

IC50: 49 nM (c-Met)[1].
分子量

548.50

Formula

C27H22F2N6O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LAH-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LAH-13018150-68-7LAH1LAH 1c-Met/HGFRApoptosisEBC-1 cellsNCI-H441 cellsantitumor activitynon-small cell lung cancerInhibitorinhibitorinhibit

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目录号：
HY-157519
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