2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor mAChR
  4. LAS190792

LAS190792  (Synonyms: AZD8999)

目录号: HY-148527
产品使用指南

摩尔计算器

LAS190792 (AZD8999) 是一种有效的毒蕈碱 (muscarinic) 拮抗剂和 β2-肾上腺素能受体 (β2-adrenoceptor) 激动剂，对 M1, M2, M3, M4, M5, β1, β2, β3 的pIC50 值分别为 8.9, 8.8, 8.8, 9.2, 8.2, 7.5, 9.1, 5.6。LAS190792 可用作支气管扩张剂。

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LAS190792 Chemical Structure

LAS190792 Chemical Structure

CAS No. : 1347232-69-2

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规格 是否有货
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LAS190792 相关抗体

Top Publications Citing Use of Products

查看 Adrenergic Receptor 亚型特异性产品:

查看所有亚型
α adrenergic receptor β adrenergic receptor

查看 mAChR 亚型特异性产品:

查看所有亚型
mAChR1 mAChR2 mAChR3 mAChR4 mAChR5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LAS190792 (AZD8999) is a potent muscarinic antagonist and β2-adrenoceptor agonist with pIC50 8.9, 8.8, 8.8, 9.2, 8.2, 7.5, 9.1, 5.6 for M1, M2, M3, M4, M5, β1, β2, β3, respectively. LAS190792 can be used as a bronchodilator[1].

IC50 & Target

β1 adrenoceptor

7.5 (pIC50)

β2 adrenoceptor

9.1 (pIC50)

β3 adrenoceptor

5.6 (pIC50)

mAChR1

8.9 (pIC50)

mAChR2

8.8 (pIC50)

mAChR3

8.8 (pIC50)

mAChR4

9.2 (pIC50)

mAChR5

8.2 (pIC50)

Clinical Trial
分子量

811.36

Formula

C39H43ClN4O9S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LAS190792 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LAS1907921347232-69-2AZD8999LAS 190792LAS-190792AZD 8999AZD-8999Adrenergic ReceptormAChRBeta ReceptorMuscarinic acetylcholine receptorInhibitorinhibitorinhibit

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