2. PROTAC Protein Tyrosine Kinase/RTK
  3. PROTACs RET
  4. LDD39

LDD39 是一种靶向降解 RET 蛋白的 PROTAC，能够在体内实现对总 RET (tRET) 蛋白的强效且持续的降解，并抑制磷酸化 RET (pRET) 信号传导。LDD39 由 E3 连接酶配体 (HY-170371) 和 靶蛋白配体 (HY-170373) 通过 Linker (HY-30105) 连接形成 (E3 连接酶配体＋Linker: HY-170374 )。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

LDD39 Chemical Structure

LDD39 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

LDD39 相关抗体

Top Publications Citing Use of Products

查看 PROTACs 亚型特异性产品:

查看所有亚型
von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LDD39 is a PROTAC targeting RET protein, capable of achieving robust and sustained degradation of total RET (tRET) protein in vivo and inhibiting phosphorylated RET (pRET) signaling. LDD39 is formed by conjugating an E3 ligase ligand (HY-170371) and a target protein ligand (HY-170373) through a linker (HY-30105) (E3 ligase ligand＋Linker: HY-170374)[1].

分子量

1008.12

Formula

C55H59F2N11O6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LDD39 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LDD39LDD 39LDD-39PROTACsRETInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
LDD39
目录号：
HY-159967
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z