PROTACs Inhibitors

von Hippel-Lindau (VHL)

Cereblon

MDM2

cIAP1

PROTACs Degraders, Inhibitors & Modulators

Product Name	von Hippel-Lindau (VHL)	Cereblon	MDM2	cIAP1	Purity
FKBP12 PROTAC dTAG-13		Cereblon			99.75%
LLC0424		Cereblon			98.42%
dBET1		Cereblon			99.24%
dTAGV-1 TFA	VHL				99.92%
dCBP-1		Cereblon			99.44%
MD-224			MDM2, IC₅₀: 1 nM		98.47%
SD-36		Cereblon			99.73%
DT2216	VHL				99.97%
LC-2	VHL				98.04%
BSJ-4-116		Cereblon			98.73%
TL12-186		Cereblon			99.63%
ZXH-3-26		Cereblon			98.90%
PROTAC-O4I2		Cereblon			99.66%
BSJ-03-123		Cereblon			98.12%
MS67	VHL				98.73%
ARCC-4	VHL				99.88%
FKBP12 PROTAC dTAG-7		Cereblon			99.07%
PROTAC CDK2/9 Degrader-1		Cereblon			99.85%
PROTAC AR-V7 degrader-1	VHL				99.34%
MS4078		Cereblon			99.63%
NX-5948		Cereblon			99.33%
ACBI2	VHL, EC₅₀: 7 nM				99.76%
XY028-140		Cereblon			98.42%
PROTAC K-Ras Degrader-1		Cereblon			98.05%
PROTAC RIPK degrader-2	VHL				99.48%
INY-03-041		Cereblon			99.74%
JB170		Cereblon			98.97%
CP-10		Cereblon			98.22%
SJF620		Cereblon			98.98%
CFT1946		Cereblon			99.84%
BI-3663		Cereblon			99.90%
JH-XI-10-02		Cereblon			99.82%
PROTAC BRD9 Degrader-1		CRBN-DDB1, IC₅₀: 48.9 nM
FKBP12 PROTAC RC32		Cereblon			98.58%
MS4322	VHL				98.28%
GNE-987	VHL				99.91%
PROTAC IRAK4 degrader-1		Cereblon			99.72%
dFKBP-1		Cereblon
PROTAC CRBN Degrader-1	VHL	Cereblon			99.84%
SJ10542		Cereblon			99.92%
PROTAC Bcl-xL degrader-2	VHL				98.16%
GMB-475	VHL				98.98%
CRBN-6-5-5-VHL		Cereblon, DC₅₀: 1.5 nM			99.98%
ARD-266	VHL
PROTAC HSP90 degrader BP3		Cereblon			98.56%
MS170		CRBN-DDB1			99.72%
XZ739		Cereblon			99.06%
C004019	VHL				99.37%
PROTAC MDM2 Degrader-3			MDM2
TL13-112		Cereblon, IC₅₀: 2.4 μM			98.15%
MD-222			MDM2		99.81%
SIAIS178	VHL				99.36%
Homo-PROTAC cereblon degrader 1		Cereblon			99.43%
PROTAC RIPK degrader-6		Cereblon			99.97%
PROTAC PD-1/PD-L1 degrader-1		Cereblon			99.52%
PROTAC CBP/P300 Degrader-1		Cereblon			98.30%
ZXH-4-130 TFA	VHL				99.71%
MG-277		Cereblon			98.66%
Homo-PROTAC pVHL30 degrader 1	VHL				99.40%
PROTAC ERRα Degrader-3	VHL				98.82%
PROTAC MDM2 Degrader-2			MDM2
PROTAC RAR Degrader-1				cIAP1
GBD-9		Cereblon			99.76%
SR-1114		Cereblon			99.04%
PROTAC EED degrader-1	VHL				98.27%
SJFα	VHL				99.61%
PROTAC EED degrader-2	VHL				99.90%
Tz-Thalidomide		Cereblon			98.01%
ARD-61	VHL				99.68%
MS154		Cereblon			98.80%
PROTAC FKBP Degrader-3	VHL				99.48%
TD-165		Cereblon, DC₅₀: 20.4 nM			99.41%
CCT367766 formic		CRBN-DDB1, IC₅₀: 490 nM			98.02%
MI-389		Cereblon			99.34%
MS4322 (isomer)	VHL				99.22%
MZP-54	VHL				98.16%
TL13-12		Cereblon, IC₅₀: 1.2 μM			98.06%
MS4077		Cereblon			99.49%
PROTAC ERα Degrader-2				cIAP1	98.88%
PROTAC MDM2 Degrader-1			MDM2		98.11%
DP-C-4		Cereblon			98.15%
PROTAC PARP1 degrader			MDM2		99.74%
PROTAC ER Degrader-4	VHL				98.22%
PZ703b	VHL				98.47%
Nampt degrader-2	VHL				99.41%
OARV-771	VHL				98.33%
PROTAC AR Degrader-4 TFA				cIAP1	99.26%
INY-03-041 trihydrochloride		Cereblon			99.27%
Thalidomide-NH-CBP/p300 ligand 2		Cereblon			98.55%
Dovitinib-RIBOTAC		Cereblon			98.93%
HDAC6 degrader-3		Cereblon			98.60%
PROTAC AR Degrader-4				cIAP1
SJF620 hydrochloride		Cereblon			99.28%
PROTAC EGFR degrader 9		Cereblon
MS33	VHL
TD-428		Cereblon
MS8847	VHL
PROTAC EGFR degrader 11		CRBN-DDB1, Ki: 36 nM
SIAIS039		Cereblon
PROTAC ERRα Degrader-2			MDM2
XY-06-007		Cereblon
MS98	VHL
PROTAC BRD4 Degrader-2		Cereblon
PROTAC ERRα Degrader-1			MDM2
CCT367766		CRBN-DDB1, IC₅₀: 490 nM
PROTAC SMARCA2 degrader-30		Cereblon
PROTAC Bcl-xL degrader-3	VHL
PROTAC PD-L1 degrader-1		Cereblon, Kd: 131.77 μM
(S)-GNE-987	VHL
Abd110		Cereblon
PROTAC FLT-3 degrader 4		Cereblon
SJ46420	VHL
SA-PA		Cereblon
ZXH-4-130	VHL
PROTAC Bcl-xL degrader-1				cIAP1
NU223612		Cereblon
UNC9036	VHL
SIAIS562055		Cereblon
PROTAC BRAF-V600E degrader-2		Cereblon
PROTAC MDM2 Degrader-4			MDM2
PROTAC TG2 degrader-1	VHL
RIP2 Kinase Inhibitor 4				cIAP1
SA-VA	VHL
PROTAC EGFR degrader 10		CRBN-DDB1, Ki: 37 nM
PROTAC SOS1 degrader-3		Cereblon
SJ46421	VHL
PROTAC SMARCA2 degrader-3		Cereblon
PROTAC BRD2/BRD4 degrader-1		Cereblon
SJFδ	VHL

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