2. PROTAC Epigenetics
  3. PROTACs Epigenetic Reader Domain
  4. PROTAC BRD9 Degrader-1

PROTAC BRD9 Degrader-1 是一种由Cereblon配体和BRD9配体相连的PROTAC，可用作研究 BAF 复合物的选择性探针。

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PROTAC BRD9 Degrader-1 Chemical Structure

PROTAC BRD9 Degrader-1 Chemical Structure

CAS No. : 2097971-01-0

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规格 价格 是否有货
1 mg ￥4400
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5 mg 现货 询问价格 & 货期

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PROTAC BRD9 Degrader-1 相关抗体

Top Publications Citing Use of Products

查看 PROTACs 亚型特异性产品:

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PROTAC BRD9 Degrader-1 is a PROTAC connected by ligands for Cereblon and BRD9 (IC50=13.5 nM), which can be used as a selective probe useful for the study of BAF complex biology[1].

IC50 & Target[1]

BRD9

13.5 nM (IC50)

BRD4

3.78 μM (IC50)

CRBN-DDB1

48.9 nM (IC50)

体外研究
(In Vitro)

PROTAC BRD9 Degrader-1 (Compound 1) 抑制 BRD9、BRD4 和 CRBN-DDB1，IC50 分别为 13.5 nM、3.78 μM 和 48.9 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PROTAC BRD9 Degrader-1 相关抗体:
分子量

903.98

Formula

C42H45N7O12S2
CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

纯度 & 产品资料
参考文献

PROTAC BRD9 Degrader-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PROTAC BRD9 Degrader-12097971-01-0PROTACsEpigenetic Reader DomainInhibitorinhibitorinhibit

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产品名称：
PROTAC BRD9 Degrader-1
目录号：
HY-103632
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