2. Membrane Transporter/Ion Channel
  3. Na+/K+ ATPase
  4. Leminoprazole

Leminoprazole  (Synonyms: NC 1300O3)

目录号: HY-105094
产品使用指南

摩尔计算器

Leminoprazole (NC 1300O3) 是 acid pump，H+，K+-ATPase 的抑制剂。Leminoprazole 可以刺激胃粘液的分泌和合成，减轻胃溃疡。Leminoprazole 具有口服活性。

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Leminoprazole Chemical Structure

Leminoprazole Chemical Structure

CAS No. : 104340-86-5

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Leminoprazole 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Leminoprazole (NC 1300O3) is an inhibitor for acid pump, H+ K+-ATPase,. Leminoprazole stimulates the secretion and synthesis of gastric mucus, attenuates gastric ulcers. Leminoprazole is orally active[1][2][3].

体外研究
(In Vitro)

Leminoprazole 通过形成共价二硫键不可逆地抑制兔胃囊泡中的 H+,K+-ATPase，IC50 为 5.3 和 19 μM[1]。
Leminoprazole 抑制组胺、卡巴胆碱、胃泌素和 db-cAMP 刺激的酸分泌，IC50 分别为 0.4，0.35，0.25 和 0.56 μM[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Leminoprazole 相关抗体:
体内研究
(In Vivo)

Leminoprazole (10-90 mg/kg，口服，单剂量) 在 Donryu 大鼠模型中促进胃粘液合成，抑制胃酸分泌[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Donyru rats model[3]
Dosage: 10-90 mg/kg
Administration: p.o., single dose
Result: Increased levels of glucosamine, decreased acid secretion.
分子量

341.47

Formula

C19H23N3OS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Leminoprazole 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Leminoprazole104340-86-5NC 1300O3Na+/K+ ATPaseSodium potassium pumpgastric secretionDonryu ratorally activeInhibitorinhibitorinhibit

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