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Lipoxin B4 methyl ester  (Synonyms: LXB4 methyl ester)

目录号: HY-134123
产品使用指南

Lipoxin B4 methyl ester (LXB4 methyl ester) 是跨细胞代谢物 LXB4 的脂溶性前药形式。LXB4 是 LXA4 的位置异构体,由人类白细胞代谢 15-HETE 或 15-HpETE 产生。浓度为 100 nM 时,LXB4 可抑制由白三烯 B4 刺激的多形核白细胞 (PMN) 迁移,并抑制 LTB4 诱导的 PMN 粘附,IC50 值为 0.3 nM。

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Lipoxin B4 methyl ester Chemical Structure

Lipoxin B4 methyl ester Chemical Structure

CAS No. : 97589-07-6

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  • 生物活性

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生物活性

Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4. LXB4 is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 (LTB4; Item No. 20110) and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.

分子量

366.49

Formula

C21H34O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Lipoxin B4 methyl ester 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Lipoxin B4 methyl ester
目录号:
HY-134123
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