1. 诱导疾病模型产品 Immunology/Inflammation
  2. 免疫与炎症疾病模型 Toll-like Receptor (TLR) MyD88
  3. LPS-PG

LPS-PG 是一种来自牙龈卟啉单胞菌 (P. gingivalis) 的脂多糖。LPS-PG 是牙周病发生机制中的重要毒力因子,需要通过 Toll 样受体 2 (TLR2) 来激活免疫细胞,而非大肠杆菌 (E. coli) 的受体 Toll 样受体 4 (TLR4)。来自 LPS-PG 的一种脂蛋白被证明是 TLR2 介导的细胞激活的主要成分。

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LPS-PG Chemical Structure

LPS-PG Chemical Structure

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2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥11500
1 - 2 周
5 mg   询价  
10 mg   询价  

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查看 Toll-like Receptor (TLR) 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LPS-PG is a lipopolysaccharide from Porphyromonas gingivalis (P. gingivalis). LPS-PG is an important virulence factor in the pathogenesis of periodontal disease and activates immune cells via Toll-like receptor 2 (TLR2), rather than the receptor for Escherichia coli (E. coli), Toll-like receptor 4 (TLR4). A lipoprotein from LPS-PG has been shown to be the major component responsible for TLR2-mediated cell activation[1][2].

体外研究
(In Vitro)

LPS-PG (1 μg/mL, 12 h) 在 HGF-1 细胞中可有效诱导急性炎症[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: HGF-1
Concentration: 1 μg/mL
Incubation Time: 18 h
Result: Increased the protein expression levels of iNOS and COX-2.
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
LPS-PG
目录号:
HY-164173
需求量: