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  4. LY86057

LY86057是一种无N1取代基的 ergoline 衍生物，对于猪、松鼠猴和人类5-HT2受体的亲和力比大鼠高，是5-HT2受体的拮抗剂。在研究物种间对一系列ergolines的识别差异时，发现LY86057对5-HT2受体的选择性较高。与LY53857相比，即使N1取代基仅为甲基，LY108742也会导致化合物对大鼠5-HT2受体的亲和力更高。

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LY86057 Chemical Structure

LY86057 Chemical Structure

CAS No. : 148966-66-9

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LY86057 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LY86057 is an ergoline derivative without N1 substituents. It has higher affinity for porcine, squirrel monkey and human 5-HT2 receptors than rats and is an antagonist of 5-HT2 receptors. When studying the differences in recognition of a series of ergolines between species, LY86057 was found to be more selective for 5-HT2 receptors. Compared with LY53857, LY108742 resulted in a higher affinity for rat 5-HT2 receptors even when the N1 substituent was only methyl.

分子量

342.43

Formula

C20H26N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LY86057 相关分类

  • 摩尔计算器

  • 稀释计算器

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This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY86057148966-66-9LY 86057LY-86057OthersInhibitorinhibitorinhibit

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