1. PROTAC
  2. PROTAC Linkers
  3. m-PEG4-Tos

m-PEG4-Tos 是水飞蓟宾醚的衍生物,来源于专利 CN105037337A (化合物 III-b)。m-PEG4-Tos 是基于 PEG 的 PROTAC 接头,可用于合成水飞蓟素 (HY-W043277)。

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m-PEG4-Tos Chemical Structure

m-PEG4-Tos Chemical Structure

CAS No. : 62921-76-0

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规格 价格 是否有货
100 mg ¥180
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500 mg ¥264
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1 g ¥420
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5 g ¥1470
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查看 PROTAC Linkers 亚型特异性产品:

  • 生物活性

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  • 参考文献

生物活性

m-PEG4-Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-b). m-PEG4-Tos is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1].

IC50 & Target[1]

PEGs

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

362.44

Formula

C16H26O7S

CAS 号
性状

液体(密度:1.164±0.06 g/cm3

颜色

Colorless to light yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
m-PEG4-Tos
目录号:
HY-114661
需求量: