1. Anti-infection
  2. Fungal
  3. Macrocarpal C

Macrocarpal C 可以从蓝桉新鲜叶的 95% 乙醇提取物中分离出来。Macrocarpal C 通过增加真菌膜的渗透性来抑制须癣菌的生长。Macrocarpal C 增加细胞内 ROS 的产生并诱导 DNA 碎片化导致细胞凋亡

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Macrocarpal C Chemical Structure

Macrocarpal C Chemical Structure

CAS No. : 142628-53-3

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1 mg ¥3500
1 - 2 周
5 mg 现货 1 - 2 周
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Macrocarpal C can be isolated from the 95 % ethanol extract of fresh leaves of E. globulus. Macrocarpal C inhibits the growth of T. mentagrophytes via an increase in the permeability of the fungal membrane. Macrocarpal C increases the production of intracellular ROS and? induces apoptosis as a consequence of DNA fragmentation[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
< 10 μM
Compound: Macrocarpal C
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay
[PMID: 27142786]
HL-60 IC50
< 10 μM
Compound: Macrocarpal C
Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay
Cytotoxicity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay
[PMID: 27142786]
分子量

454.60

Formula

C28H38O5

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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产品名称:
Macrocarpal C
目录号:
HY-N3344
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