2. Neuronal Signaling
  3. Monoamine Oxidase
  4. MAO-B-IN-16

MAO-B-IN-16 是一种选择性的单胺氧化酶 B (MAO-B) 抑制剂，其 IC50 值为 1.55 µM。MAO-B-IN-16 可用于中枢神经紊乱，如帕金森病的研究。

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MAO-B-IN-16 Chemical Structure

MAO-B-IN-16 Chemical Structure

CAS No. : 1021238-13-0

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MAO-B-IN-16 相关抗体

Top Publications Citing Use of Products

查看 Monoamine Oxidase 亚型特异性产品:

查看所有亚型
MAO-A MAO-B

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MAO-B-IN-16 is a selective monoamine oxidase B (MAO-B) inhibitor, with an IC50 of 1.55 µM. MAO-B-IN-16 can be used in the study of central nervous disorders, such as parkinson's disease[1].

IC50 & Target

hMAO-B

1.55 μM (IC50)

hMAO-A

＞100 μM (IC50)

体外研究
(In Vitro)

MAO-B-IN-16 (compound 4h) (10 μM; 24 h) has no cytotoxic effect on human neuroblastoma cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MAO-B-IN-16 相关抗体:

Cell Viability Assay[1]

Cell Line: SH-SY5Y cells
Concentration: 10 μM
Incubation Time: 24 h
Result: Showed no cytotoxic effect on cells with cellular viability of 99%.
分子量

297.35

Formula

C18H19NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MAO-B-IN-16 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MAO-B-IN-161021238-13-0Monoamine OxidaseMAOmonoamine oxidaseneural transmissiondopamineparkinson’s diseaseSH-SY5YInhibitorinhibitorinhibit

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目录号：
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