2. Anti-infection
  3. Bacterial
  4. MBX-1066

MBX 1066 是一种有效的抗菌剂。MBX 1066 对 Mycobacterium tuberculosis 有抑制作用。MBX 1066 在小鼠中表现出抗菌活性。

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MBX-1066 Chemical Structure

MBX-1066 Chemical Structure

CAS No. : 868971-24-8

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MBX-1066 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MBX 1066 is a potent antibacterial agent. MBX 1066 shows inhibition for Mycobacterium tuberculosis. MBX 1066 shows antibacterial activity in mice[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HeLa CC50
3 μg/mL
Compound: MBX-1066, NSC-317881
Cytotoxicity against human HeLa cells after 3 days by MTS assay in presence of 10% fetal calf serum
Cytotoxicity against human HeLa cells after 3 days by MTS assay in presence of 10% fetal calf serum
[PMID: 19635954]
HeLa CC50
32.5 μg/mL
Compound: 1066
Cytotoxicity against human HeLa cells by MTS assay
Cytotoxicity against human HeLa cells by MTS assay
[PMID: 24969013]
HeLa CC50
33 μg/mL
Compound: MBX-1066
Cytotoxicity against HeLa cells after 3 days by MTS assay
Cytotoxicity against HeLa cells after 3 days by MTS assay
[PMID: 20625154]
体外研究
(In Vitro)

MBX 1066 对 HeLa 细胞表现出细胞毒性，CC50 值为 33 µg/mL[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

MBX-1066 相关抗体:
体内研究
(In Vivo)

MBX 1066 (1, 10 mg/kg; i.v.; single dose, one hour post infection) 表现出抗菌活性并能提高小鼠存活率[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ICR/Swiss Webster mice (Staphylococcus aureus strain NRS384) [1]
Dosage: 1, 10 mg/kg
Administration: I.v.; single dose, one hour post infection
Result: Increased the survival in a dose-dependent maner.
分子量

444.53

Formula

C28H24N6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MBX-1066 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MBX-1066868971-24-8MBX1066MBX 1066BacterialHeLa cellsStaphylococcus aureusMycobacterium tuberculosisantibacterialcytotoxicityInhibitorinhibitorinhibit

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目录号：
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