2. Academic Validation
  3. New bioactive metabolites from a freshwater isolate of the fungus Kirschsteiniothelia sp

New bioactive metabolites from a freshwater isolate of the fungus Kirschsteiniothelia sp

  • J Nat Prod. 1992 Aug;55(8):1093-9. doi: 10.1021/np50086a010.
G K Poch 1,  J B Gloer,  C A Shearer
Affiliations

Affiliation

  • 1 Department of Chemistry, University of Iowa, Iowa City 52242.
PMID: 1431934 DOI: 10.1021/np50086a010
Abstract

The new cytotoxic naphthoquinone dimer kirschsteinin [5], two new chlorinated diphenyl ethers 8 and 9, three known naphthoquinone derivatives 1, 2, and 7, a monoacetyl derivative of 2, and the (-)-enantiomer of O-methylasparvenone [4], have been isolated from a previously undescribed species of Kirschsteiniothelia. The structures of these compounds were assigned primarily by nmr studies and by spectral comparisons.

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