2. Academic Validation
  3. Iridoids from the green leaves of Eucommia ulmoides

Iridoids from the green leaves of Eucommia ulmoides

  • J Nat Prod. 2007 Aug;70(8):1312-6. doi: 10.1021/np0780046.
Chika Takamura 1,  Tetsuya Hirata,  Taro Ueda,  Masateru Ono,  Hiroyuki Miyashita,  Tsuyoshi Ikeda,  Toshihiro Nohara
Affiliations

Affiliation

  • 1 Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan.
PMID: 17691745 DOI: 10.1021/np0780046
Abstract

The bark of Eucommia ulmoides is a well-known crude drug in oriental medicine, and its leaves have been consumed as a beverage. From the green leaves of this plant, three new Iridoids (1-3) were isolated, together with 12 known compounds. Compound 1 is the first iridoid possessing a saturated bond between C-3 and C-4 and having an ether linkage between C-3 and C-2 of the glucose unit. Furthermore, 2 and 3 may be regarded as the first naturally occurring conjugates of an iridoid and an amino acid.

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