2. Academic Validation
  3. Imidazo[2,1-b]thiazoles: multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases

Imidazo[2,1-b]thiazoles: multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases

  • Bioorg Med Chem Lett. 2010 Apr 15;20(8):2452-5. doi: 10.1016/j.bmcl.2010.03.015.
Steve D Fidanze 1,  Scott A Erickson,  Gary T Wang,  Robert Mantei,  Richard F Clark,  Bryan K Sorensen,  Nwe Y Bamaung,  Peter Kovar,  Eric F Johnson,  Kerren K Swinger,  Kent D Stewart,  Qian Zhang,  Lora A Tucker,  William N Pappano,  Julie L Wilsbacher,  Jieyi Wang,  George S Sheppard,  Randy L Bell,  Steven K Davidsen,  Robert D Hubbard
Affiliations

Affiliation

  • 1 Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064, USA. steve.fidanze@abbott.com
PMID: 20346655 DOI: 10.1016/j.bmcl.2010.03.015
Abstract

The design and Enzyme activities of a novel class of imidazo[2,1-b]thiazoles is presented.

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