2. Academic Validation
  3. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome

Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome

  • J Int Med Res. 1990 May-Jun;18(3):201-9. doi: 10.1177/030006059001800304.
I Caruso 1,  P Sarzi Puttini,  M Cazzola,  V Azzolini
Affiliations

Affiliation

  • 1 Rheumatology Unit, L. Sacco Hospital, Milan, Italy.
PMID: 2193835 DOI: 10.1177/030006059001800304
Abstract

A double-blind, placebo-controlled study of the efficacy and tolerability of 5-hydroxytryptophan (5-HTP) was conducted in 50 patients with primary fibromyalgia syndrome. All the clinical parameters studied were significantly improved by treatment with 5-HTP and only mild and transient side-effects were reported. Further controlled studies are required to define properly the value of 5-HTP in patients with primary fibromyalgia syndrome.

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