1. Academic Validation
  2. Lanostane and hopane triterpenes from the entomopathogenic fungus Hypocrella sp. BCC 14524

Lanostane and hopane triterpenes from the entomopathogenic fungus Hypocrella sp. BCC 14524

  • J Nat Prod. 2011 Oct 28;74(10):2143-50. doi: 10.1021/np200429b.
Masahiko Isaka 1 Panida Chinthanom Malipan Sappan Rungtiwa Chanthaket J Jennifer Luangsa-ard Samran Prabpai Palangpon Kongsaeree
Affiliations

Affiliation

  • 1 National Center for Genetic Engineering and Biotechnology (BIOTEC), 113 Thailand Science Park, Phaholyothin Road, Klong Luang, Pathumthani 12120, Thailand. isaka@biotec.or.th
Abstract

Seven new lanostane-type Triterpenes, hypocrellols A-G (1-7), and six new hopane-type Triterpenes, 7β,15α-dihydroxy-22(29)-hopene (8), 3β,7β-dihydroxy-22(29)-hopene (9), 3β-acetoxy-15α-hydroxy-22(29)-hopene (10), 3β,7β,15α,22-tetrahydroxyhopane (11), 3β-acetoxy-7β,15α,22-trihydroxyhopane (12), and 7β,15α,22-trihydroxyhopane (13), were isolated from the scale insect pathogenic fungus Hypocrella sp. BCC 14524. The structures of the new compounds were elucidated by analyses of the NMR spectroscopic and mass spectrometry data. The structure of 1 was confirmed by X-ray crystallography.

Figures