2. Academic Validation
  3. Isoforsythiaside, an antioxidant and antibacterial phenylethanoid glycoside isolated from Forsythia suspensa

Isoforsythiaside, an antioxidant and antibacterial phenylethanoid glycoside isolated from Forsythia suspensa

  • Bioorg Chem. 2012 Feb;40(1):87-91. doi: 10.1016/j.bioorg.2011.09.005.
Huanhuan Qu 1,  Yongmin Zhang 2,  Xiaoyun Chai 3,  Wenji Sun 4
Affiliations

Affiliations

  • 1 Université Pierre & Marie Curie-Paris 6, Institut Parisien de Chimie Moléculaire, UMR 7201 CNRS, 4 Place Jussieu, 75005 Paris, France; Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, PR China.
  • 2 Université Pierre & Marie Curie-Paris 6, Institut Parisien de Chimie Moléculaire, UMR 7201 CNRS, 4 Place Jussieu, 75005 Paris, France.
  • 3 Department of Organic Chemistry, College of Pharmacy, Second Military Medical University, Shanghai 200433, PR China.
  • 4 Biomedicine Key Laboratory of Shaanxi Province, Northwest University, Xi'an 710069, PR China. Electronic address: aiby116@163.com.
PMID: 22014602 DOI: 10.1016/j.bioorg.2011.09.005
Abstract

The isolation, structural elucidation, antioxidant effect and Antibacterial activity of isoforsythiaside, a novel phenylethanoid glycoside isolated from Forsythia suspensa, were described. The antioxidant activity was estimated using the 1-diphenyl-2-picrylhydrazyl scavenging activity method and the in vitro antimicrobial activity was evaluated by the microtitre plate method. The results showed that this compound had strong activities. Owing to these properties, the study can be further extended to exploit for the possible application of isoforsythiaside as the alternative antioxidants and Antibacterial agents from natural origin.

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