2. Academic Validation
  3. Antineoplastic agents, 195. Isolation and structure of aceratioside from Aceratium megalospermum

Antineoplastic agents, 195. Isolation and structure of aceratioside from Aceratium megalospermum

  • J Nat Prod. 1990 Sep-Oct;53(5):1187-92. doi: 10.1021/np50071a009.
S B Singh 1,  G R Pettit
Affiliations

Affiliation

  • 1 Cancer Research Institute, Arizona State University, Tempe 85287.
PMID: 2292686 DOI: 10.1021/np50071a009
Abstract

A new tetralin glucoside [1], named aceratioside, has been found to be a weakly cytostatic (PS ED50 9 micrograms/ml) constituent in leaves produced by the Australian rain forest tree Aceratium megalospermum. Structural determination of aceratioside was primarily accomplished with results from a series of acetylation, methylation, and high field nmr (including heteronuclear multiple bond correlation) experiments.

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