2. Academic Validation
  3. Discovery of NVP-LEQ506, a second-generation inhibitor of smoothened

Discovery of NVP-LEQ506, a second-generation inhibitor of smoothened

  • ChemMedChem. 2013 Aug;8(8):1261-5. doi: 10.1002/cmdc.201300217.
Stefan Peukert 1,  Feng He,  Miao Dai,  Rui Zhang,  Yingchuan Sun,  Karen Miller-Moslin,  Michael McEwan,  Bharat Lagu,  Kate Wang,  Naeem Yusuff,  Aaron Bourret,  Arun Ramamurthy,  Wieslawa Maniara,  Adam Amaral,  Anthony Vattay,  Anlai Wang,  Ribo Guo,  Jing Yuan,  John Green,  Juliet Williams,  Silvia Buonamici,  Joseph F Kelleher 3rd,  Marion Dorsch
Affiliations

Affiliation

  • 1 Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA. stefan.peukert@novartis.com.
PMID: 23821351 DOI: 10.1002/cmdc.201300217
Keywords

antitumor agents; hedgehog signaling; medicinal chemistry; pyridazines; smoothened inhibitors.

Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-18636
    98.15%, Smo 抑制剂
    Smo
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z