2. Academic Validation
  3. Steroidal Saponins from the Rhizomes of Anemarrhena asphodeloides

Steroidal Saponins from the Rhizomes of Anemarrhena asphodeloides

  • Molecules. 2016 Aug 17;21(8):1075. doi: 10.3390/molecules21081075.
Bing-You Yang 1,  Jing Zhang 2,  Yan Liu 3,  Hai-Xue Kuang 4
Affiliations

Affiliations

  • 1 Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, China. ybywater@163.com.
  • 2 Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, China. zhangjing823@yeah.net.
  • 3 Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, China. lifeliuyan@163.com.
  • 4 Key Laboratory of Chinese Materia Medica (Ministry of Education), Heilongjiang University of Chinese Medicine, Harbin 150040, China. hxkuang@yahoo.com.
PMID: 27548119 DOI: 10.3390/molecules21081075
Abstract

Four new steroid saponins 1-4 were isolated from the rhizomes of Anemarrhena asphodeloides (Asparagaceae), as well as four known saponins: anemarsaponin B (5) timosaponin D (6), timosaponin E1 (7) anemarsaponin B II (8). Their structures were established through UV and NMR as well as MS data. All the compounds were evaluated for cytotoxicity against HepG2 and SGC7901 human Cancer lines. Compounds 3 and 7 displayed medium antiproliferative activities on HepG2 and SGC7901 cells, with IC50 values of 43.90 and 57.90 μM, respectively.

Keywords

Asparagaceae; MTT; cytotoxicity; furostanol saponin; spirostanol saponin.

Figures
Products
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z