Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen

Affiliations

• 1 1 Department of Molecular and Cell Biology and Department of Chemistry, California Institute of Quantitative Biosciences and Howard Hughes Medical Institute, University of California, Berkeley, CA, USA.
• 2 Plexxikon Inc., Berkeley, CA, USA.
• 3 3 Department of Pharmaceutical Chemistry, Small Molecule Discovery Center, University of California, San Francisco, CA, USA.
• 4 Omniox Inc., San Carlos, CA, USA.
• 5 Janssen Pharmaceuticals Inc., Titusville, NJ, USA.
• 6 4 Department of Medicine, Rosalind Russell and Ephrain P. Engleman Rheumatology Research Center for Arthritis and Howard Hughes Medical Institute, University of California, San Francisco, CA, USA.
• 7 2 Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.