Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13

Affiliations

• 1 Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA.
• 2 Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO, USA.
• 3 Center for Tuberculosis Research, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
• 4 Department of Immunology and Infectious Disease, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
• 5 Structure-guided Drug Discovery Coalition, SGC Toronto, ON, Canada.
• 6 Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, College of Life Sciences, University of Dundee, Dundee, UK.
• 7 Department of Computer Science and Engineering, Texas A&M University, College Station, TX, USA.
• 8 NRF Centre of Excellence for Biomedical TB Research and the South African MRC Centre for Molecular and Cellular Biology, Division of Molecular Biology and Human Genetics, Stellenbosch University, Tygerberg, South Africa.
• 9 Institute of Medical Microbiology, National Center for Mycobacteria, University of Zurich, Zurich, Switzerland.
• 10 Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA. Electronic address: sacchett@tamu.edu.