2. Academic Validation
  3. Dual effects of propyl gallate and its methylglyoxal adduct on carbonyl stress and oxidative stress

Dual effects of propyl gallate and its methylglyoxal adduct on carbonyl stress and oxidative stress

  • Food Chem. 2018 Nov 1;265:227-232. doi: 10.1016/j.foodchem.2018.04.045.
Hengqing Cui 1,  Fei Tao 2,  Yu Hou 1,  Yongling Lu 1,  Tiesong Zheng 1,  Shengmin Sang 3,  Lishuang Lv 4
Affiliations

Affiliations

  • 1 Department of Food Science and Technology, Nanjing Normal University, 122# Ninghai Road, Nanjing 210097, PR China.
  • 2 College of Standardization, China Jiliang University, 258# Xueyuan Street, Hangzhou 310018, PR China.
  • 3 Laboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC 28081, United States. Electronic address: ssang@ncat.edu.
  • 4 Department of Food Science and Technology, Nanjing Normal University, 122# Ninghai Road, Nanjing 210097, PR China. Electronic address: lulishuang@njnu.edu.cn.
PMID: 29884377 DOI: 10.1016/j.foodchem.2018.04.045
Abstract

In the present study, we investigated the trapping of methylglyoxal (MGO) by propyl gallate (PG), a known food grade antioxidant, and the anti-carbonyl and anti-oxidative properties of the mono-MGO adduct of PG (MM-PG). Our result indicated that more than 77.5% MGO was suppressed by PG after a 30 min incubation of PG with MGO, which was much more effective than gallic acid (15.2%). For the first time, MM-PG was purified, and its structure was elucidated based on the analysis of its 1H, 13C, and 2D-NMR data. We also demonstrated that MM-PG had strong anti-oxidative and anti-carbonyl activities. Furthermore, PG could trap the MGO generated during the preparation of roasted pork, and both mono- and di- MGO adducts of PG were detected in the roasted pork system using LC/MS technique. Thus, PG could be widely applied in the food system for inhibiting the formation of both carbonyl species and oxidative species.

Keywords

Carbonyl stress; Food processing; Methylglyoxal; Oxidative stress; Propyl gallate (PubChem CID: 4947).

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