New anthracene and anthraquinone metabolites from Prismatomeris filamentosa and their antibacterial activities

An unusual, new anthracene natural product named filamentos A (1), two new anthraquinone derivatives named filamentos B (2) and C (3), together with sixteen known compounds (4-19), were isolated from the roots of the tree Prismatomeris filamentosa. Their structures were identified by analysis of mass and spectroscopic data (IR, 1D and 2D NMR). Twelve metabolites (1-6, 9, 12-14, 16-17) showed moderate Antibacterial activities against a wide range of Gram-positive and Gram-negative bacteria such as B. subtilis, B. cereus, S. aureus, E. coli, P. aeruginosa and S. sonnei.

Prismatomeris filamentosa; anthracene; anthraquinone; antibacterial.