Super-Resolution Microscopy of Chromatin

Since the advent of super-resolution microscopy, countless approaches and studies have been published contributing significantly to our understanding of cellular processes. With the aid of chromatin-specific fluorescence labeling techniques, we are gaining increasing insight into gene regulation and chromatin organization. Combined with super-resolution imaging and data analysis, these labeling techniques enable direct assessment not only of chromatin interactions but also of the function of specific chromatin conformational states.

DNA; DNA labeling; chromatin; fluorescence; nuclear architecture; single molecule localization microscopy; super-resolution microscopy.