2. Academic Validation
  3. Enzymes from Marine Polar Regions and Their Biotechnological Applications

Enzymes from Marine Polar Regions and Their Biotechnological Applications

  • Mar Drugs. 2019 Sep 23;17(10):544. doi: 10.3390/md17100544.
Stefano Bruno 1,  Daniela Coppola 2 3,  Guido di Prisco 4,  Daniela Giordano 5 6,  Cinzia Verde 7 8
Affiliations

Affiliations

  • 1 Department of Food and Drug, University of Parma, Parco Area delle Scienze 23A, 43124 Parma, Italy. stefano.bruno@unipr.it.
  • 2 Institute of Biosciences and BioResources (IBBR), CNR, Via Pietro Castellino 111, 80131 Napoli, Italy. daniela.coppola@ibbr.cnr.it.
  • 3 Department of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy. daniela.coppola@ibbr.cnr.it.
  • 4 Institute of Biosciences and BioResources (IBBR), CNR, Via Pietro Castellino 111, 80131 Napoli, Italy. guido.diprisco@ibbr.cnr.it.
  • 5 Institute of Biosciences and BioResources (IBBR), CNR, Via Pietro Castellino 111, 80131 Napoli, Italy. daniela.giordano@ibbr.cnr.it.
  • 6 Department of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy. daniela.giordano@ibbr.cnr.it.
  • 7 Institute of Biosciences and BioResources (IBBR), CNR, Via Pietro Castellino 111, 80131 Napoli, Italy. c.verde@ibp.cnr.it.
  • 8 Department of Marine Biotechnology, Stazione Zoologica Anton Dohrn, Villa Comunale, 80121 Napoli, Italy. c.verde@ibp.cnr.it.
PMID: 31547548 DOI: 10.3390/md17100544
Abstract

The Microorganisms that evolved at low temperatures express cold-adapted Enzymes endowed with unique catalytic properties in comparison to their mesophilic homologues, i.e., higher catalytic efficiency, improved flexibility, and lower thermal stability. Cold environments are therefore an attractive Research Area for the discovery of Enzymes to be used for investigational and industrial applications in which such properties are desirable. In this work, we will review the literature on cold-adapted Enzymes specifically focusing on those discovered in the bioprospecting of polar marine environments, so far largely neglected because of their limited accessibility. We will discuss their existing or proposed biotechnological applications within the framework of the more general applications of cold-adapted Enzymes.

Keywords

Arctic/Antarctic environment; biocatalysis; cold-adaptation; marine biotechnology.

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