2. Academic Validation
  3. Antibacterial and antifungal activity of liriodenine and related oxoaporphine alkaloids

Antibacterial and antifungal activity of liriodenine and related oxoaporphine alkaloids

  • J Pharm Sci. 1980 Oct;69(10):1180-3. doi: 10.1002/jps.2600691016.
C D Hufford,  A S Sharma,  B O Oguntimein
PMID: 7420287 DOI: 10.1002/jps.2600691016
Abstract

Liriodenine was evaluated for its Antibacterial and Antifungal activity against several Microorganisms. Other related oxoaporphine Alkaloids also were evaluated. Attempts to prepare oxoaporphine Alkaloids from N-acetylnoraporphines were unsuccessful, but an unexpected phenanthrene alkaloid was obtained. A novel N-demethylation reaction was noted when oxogaucine methiodide and liriodenine methiodide were treated with alumina.

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