2. Academic Validation
  3. Macrocarpals H, I, and J from the Leaves of Eucalyptus globulus

Macrocarpals H, I, and J from the Leaves of Eucalyptus globulus

  • J Nat Prod. 1996 Sep;59(9):823-7. doi: 10.1021/np9604994.
K Osawa 1,  H Yasuda,  H Morita,  K Takeya,  H Itokawa
Affiliations

Affiliation

  • 1 Department of Basic Research, Lotte Central Laboratory Co, Ltd., Saitama, Japan.
PMID: 8864235 DOI: 10.1021/np9604994
Abstract

A 50% EtOH extract of Eucalyptus globulus leaves yielded eight phloroglucinol--sesquiterpene-coupled constituents, including three novel compounds named macrocarpals, H, I, and J. Some of these compounds possessed Antibacterial activity against oral pathogenic Microorganisms with MIC values ranging from 0.20 micrograms/mL to 6.25 micrograms/mL. Inhibition of glucosyltransferase activity by these compounds was also noted.

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