2. Academic Validation
  3. Bisbenzylisoquinoline alkaloids from Stephania cepharantha and their effects on proliferation of cultured cells from the murine hair apparatus

Bisbenzylisoquinoline alkaloids from Stephania cepharantha and their effects on proliferation of cultured cells from the murine hair apparatus

  • Planta Med. 1997 Oct;63(5):425-8. doi: 10.1055/s-2006-957726.
K Nakaoji 1,  H Nayeshiro,  T Tanahashi,  Y Su,  N Nagakura
Affiliations

Affiliation

  • 1 Sunstar Inc., Osaka, Japan.
PMID: 9342946 DOI: 10.1055/s-2006-957726
Abstract

Bisbenzylisoquinoline Alkaloids were isolated from Stephania cepharantha Hayata and their proliferative activities on cultured hair cells from the murine skin were evaluated. Cepharanthine (1), cepharanoline (9), isotetrandrine (2), and berbamine (7) showed significant activities in the range of 0.01-0.1 microgram/ml, but had no activity on cultured keratinocytes or fibroblasts from the murine skin.

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