2. GPCR/G Protein Neuronal Signaling
  3. MCHR1 (GPR24)
  4. MCH(human, mouse, rat)

MCH(human, mouse, rat)  (Synonyms: Melanin-concentrating hormone(human, mouse, rat))

目录号: HY-P1205
产品使用指南

摩尔计算器

MCH (human, mouse, rat) 是一种有效的 MCH-R  的肽激动剂，与 MCH1R 和 MCH2R 结合的 IC50 值分别为 0.3nM 和 1.5 nM。MCH (human, mouse, rat) 对 CHO 细胞系中 MCH-2R 高度敏感，通过 FLIPR 监测细胞内钙动员，显示出功能性激活 MCH-1R 和 MCH-2R 的 EC50 值对分别为 3.9 nM 和 0.1 nM。

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Custom Peptide Synthesis

MCH(human, mouse, rat) Chemical Structure

MCH(human, mouse, rat) Chemical Structure

CAS No. : 128315-56-0

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MCH(human, mouse, rat) 的其他形式现货产品:

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Other Forms of MCH(human, mouse, rat):

MCH(human, mouse, rat) 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MCH (human, mouse, rat) is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively[1].

IC50 & Target

Binding IC50: 0.3 nM (MCH1R)
IC50: 1.5 nM (MCH1R)[1]
分子量

2386.84

Formula

C105H160N30O26S4
CAS 号
Sequence Shortening

DFDMLRCMLGRVYRPCWQV (Disulfide bridge:Cys7-Cys16)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MCH(human, mouse, rat) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MCH(human, mouse, rat)128315-56-0Melanin-concentrating hormone(human, mouse, rat)MCHR1 (GPR24)Melanin concentrating hormone receptor 1Inhibitorinhibitorinhibit

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