1. Neuronal Signaling
  2. Amyloid-β
  3. mcK6A1

mcK6A1 是抑制淀粉样蛋白-β () 聚集的抑制剂,能够选择性地与 Aβ42 的 16KLVFFA21 片段结合,形成延伸的 β 折叠结构,并抑制 Aβ42 寡聚体的形成。mcK6A1 可用于阿尔茨海默病和其他淀粉样蛋白相关疾病的研究。

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Custom Peptide Synthesis

mcK6A1 Chemical Structure

mcK6A1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
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250 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

mcK6A1 is an inhibitor for the aggregation of amyloid-β (), that selectively binds to the 16KLVFFA21 segment of Aβ42, forms an extended β-folded structure, and inhibits the formation of Aβ42 oligomers. mcK6A1 can be used in research of Alzheimer's disease and other amyloid-related diseases[1].

分子量

1446.65

Formula

C71H99N17O16

Sequence

cyclo{{Orn}-Thr-Leu-Trp-Tyr-Lys-{δ-Orn}-{hydrazine-(5-Amino-2-methoxybenzoic acid)-(oxalic acid)}-Lys-Tyr}

Sequence Shortening

cyclo{{Orn}-TLWYK-{δ-Orn}-{hydrazine-(5-Amino-2-methoxybenzoic acid)-(oxalic acid)}-KY}

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
mcK6A1
目录号:
HY-P10876
需求量: