1. Anti-infection
  2. SARS-CoV
  3. MERS-CoV-IN-2

MERS-CoV-IN-2 (compound 3c) 是一种 MERS-CoV 3CLpro 抑制剂 (IC50=17nM)。MERS-CoV-IN-2 通过与 3CLpro 酶的活性位点结合,特别是 S4 亚位点,来抑制酶的活性,从而展现出对 SARS-CoV-2 和 MERS-CoV 的抗病毒活性。

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MERS-CoV-IN-2 Chemical Structure

MERS-CoV-IN-2 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MERS-CoV-IN-2 (compound 3c) is a MERS-CoV 3CLpro inhibitor (IC50=17nM). MERS-CoV-IN-2 inhibits the activity of the 3CLpro enzyme by binding to the active site of the enzyme, specifically the S4 subsite, thereby exhibiting antiviral activity against SARS-CoV-2 and MERS-CoV[1].

分子量

535.03

Formula

C26H35ClN4O6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

MERS-CoV-IN-2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MERS-CoV-IN-2
目录号:
HY-162674
需求量: