2. 天然产物
  3. 酚类 内源性代谢物
  4. 单酚类
  5. Met-Enkephalin-Arg-Phe

Met-Enkephalin-Arg-Phe 是一种天然存在的具有缓解疼痛活性的七肽。

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Custom Peptide Synthesis

Met-Enkephalin-Arg-Phe Chemical Structure

Met-Enkephalin-Arg-Phe Chemical Structure

CAS No. : 73024-95-0

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规格 是否有货
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Customer Review

Met-Enkephalin-Arg-Phe 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity[1].

体内研究
(In Vivo)

Met-Enkephalin-Arg-Phe (10-100 nmol/mouse; i.c.v.; once) 在小鼠中有缓解疼痛活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Swiss Webster mice[1]
Dosage: 10-100 nmol/mouse
Administration: Intracerebralventricular injection, once
Result: Produced a dose-related inhibition of the tail-flick response. The effects peaked at 2-4 min and were dissipated by 10 min. The EC50 was 38.5 nmol/mouse.
分子量

877.02

Formula

C42H56N10O9S
CAS 号
Sequence

Tyr-Gly-Gly-Phe-Met-Arg-Phe
Sequence Shortening

YGGFMRF
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
细胞实验： 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
纯度 & 产品资料
参考文献

Met-Enkephalin-Arg-Phe 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Met-Enkephalin-Arg-Phe73024-95-0OthersInhibitorinhibitorinhibit

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产品名称：
Met-Enkephalin-Arg-Phe
目录号：
HY-P4196
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