2. Cell Cycle/DNA Damage Apoptosis
  3. DNA/RNA Synthesis Apoptosis
  4. Methoxyamine hydrochloride (Standard)

Methoxyamine hydrochloride (Standard)  (Synonyms: 甲氧基胺盐酸盐 (Standard))

目录号: HY-Y0958R 纯度: ≥98%
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摩尔计算器

Methoxyamine (hydrochloride) (Standard)是 Methoxyamine (hydrochloride) 的分析标准品。本产品用于研究及分析应用。Methoxyamine (O-Methylhydroxylamine) hydrochloride 是一种具有口服活性的、有效的碱基切除修复 (BER) 抑制剂。Methoxyamine hydrochloride 与 3-甲基嘌呤-DNA 糖基化酶 (MPG) 切除受损碱基后留下的 3' 羟基结合，从而抑制 BER 活性。Methoxyamine hydrochloride 直接与脱嘧啶 (AP) 位点结合。Methoxyamine hydrochloride 可协同增强 DNA 损伤剂的治疗效果。

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Methoxyamine hydrochloride (Standard) Chemical Structure

Methoxyamine hydrochloride (Standard) Chemical Structure

CAS No. : 593-56-6

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生物活性

Methoxyamine (hydrochloride) (Standard) is the analytical standard of Methoxyamine (hydrochloride). This product is intended for research and analytical applications. Methoxyamine (O-Methylhydroxylamine) hydrochloride is an orally active and potent base excision repair (BER) inhibitor. Methoxyamine hydrochloride binds to 3’ hydroxyl groups that are left behind by 3-methylpurine-DNA glycosylase (MPG) following excision of the damaged base and thus inhibits BER activity. Methoxyamine hydrochloride binds directly to the apyrimidinic (AP) sites. Methoxyamine hydrochloride synergistically enhances the therapeutic efficacy of DNA-damaging agents.

分子量

83.52

Formula

CH6ClNO
CAS 号
中文名称

甲氧基胺盐酸盐 (Standard)；甲氧胺盐酸盐 (Standard)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Methoxyamine hydrochloride (Standard) 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methoxyamine hydrochloride (Standard)593-56-6甲氧基胺盐酸盐 (Standard)甲氧胺盐酸盐 (Standard)DNA/RNA SynthesisApoptosisOrallybase excision repairBER3’ hydroxyl3-methylpurine-DNA glycosylaseMPGapyrimidinicAP siteDNA-damagingInhibitorinhibitorinhibit

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