1. Epigenetics
  2. METTL3
  3. METTL3-IN-2

METTL3-IN-2 (compound 28) 是 METTL3 抑制剂,IC50 值为 6.1 nM。METTL3-IN-2 抑制 Caov3 癌细胞增殖。

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METTL3-IN-2 Chemical Structure

METTL3-IN-2 Chemical Structure

CAS No. : 2767258-88-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

METTL3-IN-2 (compound 28) is a METTL3 inhibitor with an IC50 value of 6.1 nM. METTL3-IN-2 inhibits cell proliferation of Caov3 cancer cells[1].

体外研究
(In Vitro)

METTL3-IN-2 抑制 METTL3 的活性,IC50 值为 6.1 nM[1]
METTL3-IN-2 (0-30 μM; 120 h) 抑制 Caov3 细胞增殖[1]
METTL3-IN-2 (0-30 μM; 120 h) 抑制 KASUMI 细胞的生长,IC50 值为 315.8 nM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: Caov3 cell line
Concentration: 0-30 μM
Incubation Time: 120 hours
Result: Inhibited cell proliferation of Caov3 cells with an IC50 value of 102.5 nM.
分子量

454.53

Formula

C25H26N8O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
METTL3-IN-2
目录号:
HY-148468
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