1. Immunology/Inflammation Apoptosis
  2. IFNAR Tim3 TNF Receptor
  3. MG-T-19

MG-T-19 是有效的 TIM-3 抑制剂,能抑制 TIM-3PtdSerCEACAM1Gal-9 的相互作用。MG-T-19 能增加来自健康供体的外周血单个核细胞 (PBMCs) 的肿瘤坏死因子-α (TNF-α) 和干扰素-γ (IFN-γ) 的产生,并增强 PBMCs 抑制 Kasumi-1 细胞 (急性髓系白血病细胞系) 增殖的能力。

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MG-T-19 Chemical Structure

MG-T-19 Chemical Structure

CAS No. : 328540-44-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MG-T-19 is an effective TIM-3 inhibitor that can suppress the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9. MG-T-19 can increase the production of tumor necrosis factor-α (TNF-α) and interferon-γ (IFN-γ) in peripheral blood mononuclear cells (PBMCs) from healthy donors, and enhance the ability of PBMCs to inhibit the proliferation of Kasumi-1 cells (an acute myelogenous leukemia cell line)[1].

分子量

596.60

Formula

C18H8Br2ClF3N4O2S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MG-T-19
目录号:
HY-159884
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