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Milciclib maleate  (Synonyms: PHA-848125 maleate)

目录号: HY-10424A
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摩尔计算器

Milciclib (PHA-848125) maleate 是一种细胞周期依赖性激酶抑制剂，可抑制黑色素瘤细胞生长并调节参与细胞周期调控的基因表达。Milciclib maleate 已被证明可显著影响各种基因的表达，包括下调 PTTG1，从而发挥其抗增殖活性。Milciclib maleate 与 PTTG1 沉默相结合可增强 p53 突变黑色素瘤细胞对抑制的敏感性。

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Milciclib maleate Chemical Structure

Milciclib maleate Chemical Structure

CAS No. : 1253645-38-3

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Milciclib maleate 的其他形式现货产品:

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Milciclib maleate 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Milciclib (PHA-848125) maleate is a cyclin-dependent kinase inhibitor that impairs melanoma cell growth and modulates gene expression involved in cell cycle regulation. Milciclib maleate has been shown to significantly affect the expression of various genes, including down-regulating PTTG1, contributing to its antiproliferative activity. Milciclib maleate enhances sensitivity to treatment in p53 mutated melanoma cells when combined with PTTG1 silencing.

分子量

576.65

Formula

C29H36N8O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Milciclib maleate 相关分类

  • 摩尔计算器

  • 稀释计算器

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Keywords:

Milciclib1253645-38-3PHA-848125PHA848125PHA 848125OthersInhibitorinhibitorinhibit

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