2. Immunology/Inflammation Antibody-drug Conjugate/ADC Related
  3. CD276/B7-H3 ADC Antibody
  4. Mirzotamab

Mirzotamab  (Synonyms: 米佐妥单抗)

目录号: HY-P99740 纯度: ≥95.0%
COA

摩尔计算器

Mirzotamab 是一种靶向 CD276/B7-H3 的 IgG1κ 单克隆抗体，具有抗肿瘤活性。Mirzotamab 可以与 BCL 抑制剂 Clezutoclax (HY-137774) 结合形成 Mirzotamab clezutoclax (HY-P99741)，可参与紫杉烷研究复发/难治性实体瘤的研究。Mirzotamab clezutoclax (ABBV-155) 是一种靶向抗体偶联药物 (ADC)。

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CAS No. : 2229859-11-2

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规格 价格 是否有货 数量
1 mg ￥2800
In-stock
5 mg ￥7200
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

Mirzotamab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Mirzotamab is an IgG1κ monoclonal antibody targeting to CD276/B7-H3 with anti-tumor activity. Mirzotamab conjugates with Clezutoclax (HY-137774), a BCL inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane research in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted antibody drug conjugate (ADC)[1][2][3].

同型

Human IgG1 kappa
推荐同型对照抗体
种属

Chimeric; Humanized
IC50 & Target

CD276/B7-H3[1]
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

米佐妥单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Immobilized CD276/B7-H3 Protein, Human can bind Mirzotamab. The EC50 for this effect is 13.63 ng/mL.
纯度 & 产品资料

纯度: ≥95.0%

COA (264 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Mirzotamab 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Mirzotamab2229859-11-2米佐妥单抗CD276/B7-H3ADC AntibodyB7 homolog 3 proteinIgG1κ monoclonal antibodyanti-tumor activityMirzotamab clezutoclaxADCInhibitorinhibitorinhibit

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