1. Metabolic Enzyme/Protease
  2. Aldose Reductase
  3. MK181

MK181 是一种醛糖还原酶 (aldose reductase (AR)) 抑制剂,对醛糖还原酶和 AKR1B10IC50 分别为 0.71 μM 和 4.5 μM。MK181 可以结合到 AKR1B10 的外部环 A 亚口袋中。

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MK181 Chemical Structure

MK181 Chemical Structure

CAS No. : 314297-32-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MK181 is an aldose reductase (AR) inhibitor with IC50s of 0.71 μM and 4.5 μM for aldose reductase and AKR1B10, respectively. MK181 can bind into the external loop A subpocket of AKR1B10[1].

分子量

398.64

Formula

C16H13BrClNO4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MK181
目录号:
HY-122177
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