2. Cell Cycle/DNA Damage Cytoskeleton Apoptosis
  3. Microtubule/Tubulin Apoptosis
  4. Monomethyl auristatin E (Standard)

Monomethyl auristatin E (Standard)  (Synonyms: MMAE (Standard); SGD-1010 (Standard); Vedotin (Standard))

目录号: HY-15162R 纯度: ≥98%
产品使用指南

摩尔计算器

Monomethyl auristatin E (Standard) 是 Monomethyl auristatin E 的分析标准品。本产品用于研究及分析应用。Monomethyl auristatin E 是海兔毒素 10 的合成衍生物，通过抑制微管蛋白聚合而起到有效的有丝分裂抑制作用。 MMAE 广泛用作细胞毒性成分，用来制备抗体偶联活性分子 (ADCs)，可用于癌症的研究。

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Monomethyl auristatin E (Standard) Chemical Structure

Monomethyl auristatin E (Standard) Chemical Structure

CAS No. : 474645-27-7

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规格 价格 是否有货 数量
5 mg ￥585
In-stock
10 mg ￥820
In-stock
25 mg ￥1230
In-stock
50 mg ￥1600
In-stock
100 mg ￥2240
In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

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生物活性

Monomethyl auristatin E (MMAE) (Standard) is the analytical standard of Monomethyl auristatin E (HY-15162). This product is intended for research and analytical applications. Monomethyl auristatin E is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) against several different cancer types.

分子量

717.98

Formula

C39H67N5O7
CAS 号
性状

固体

颜色

White to off-white

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Monomethyl auristatin E (Standard) 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Monomethyl auristatin E (Standard)474645-27-7MMAE (Standard) SGD-1010 (Standard) Vedotin (Standard)Microtubule/TubulinApoptosisInhibitorinhibitorinhibit

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目录号：
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