2. Immunology/Inflammation
  3. NO Synthase
  4. Morachalcone A

Morachalcone A 是一种天然芳香化酶抑制剂 (IC50=4.6 mM)。Morachalcone A 也是一种植物代谢物，具有潜在的抗炎和抗癌活性。Morachalcone A 抑制脂多糖 (HY-D1056) 诱导的一氧化氮产生。

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Morachalcone A Chemical Structure

Morachalcone A Chemical Structure

CAS No. : 76472-88-3

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规格 价格 是否有货 数量
1 mg ￥11280
1 - 2 周
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Morachalcone A 相关抗体

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nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Morachalcone A is a naturally-occurring aromatase inhibitor (IC50=4.6 mM). Morachalcone A is also a plants metabolite with potential anti-inflammatory and anticancer activity. Morachalcone A inhibits Lipopolysaccharide (HY-D1056)-induced nitric oxide production[1][2][3].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
RAW264.7 IC50
16.4 μM
Compound: 3
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation after 20 hrs
Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells assessed as nitrite accumulation after 20 hrs
[PMID: 16643064]
RAW264.7 IC50
58 μM
Compound: 3
Cytotoxicity against mouse RAW264.7 cells by MTT assay
Cytotoxicity against mouse RAW264.7 cells by MTT assay
[PMID: 16643064]
体外研究
(In Vitro)

Morachalcone A 是 Maclura pomifera(奥色橘树)、Hypericum Geminiflorum 和 Broussonetia papyrifera 的代谢物[1]。
Morachalcone A 在体外培养的 RAW 264.7 细胞中对脂多糖诱导的一氧化氮产生有抑制作用[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Morachalcone A 相关抗体:
分子量

340.37

Formula

C20H20O5
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Morachalcone A 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Morachalcone A76472-88-3NO SynthaseNitric oxide synthasesNOSInhibitorinhibitorinhibit

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产品名称：
Morachalcone A
目录号：
HY-N3246
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