Morachalcone A 

Morachalcone A is a naturally-occurring aromatase inhibitor (IC₅₀=4.6 mM). Morachalcone A is also a plants metabolite with potential anti-inflammatory and anticancer activity. Morachalcone A inhibits Lipopolysaccharide (HY-D1056)-induced nitric oxide production^[1][2][3].

Morachalcone A 是 Maclura pomifera(奥色橘树)、Hypericum Geminiflorum 和 Broussonetia papyrifera 的代谢物^[1]。
Morachalcone A 在体外培养的 RAW 264.7 细胞中对脂多糖诱导的一氧化氮产生有抑制作用^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

340.37

C₂₀H₂₀O₅

76472-88-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Brandt D R, et al. The synthetic preparation of naturally-occurring aromatase inhibitors, morachalcone A, isogemichalcone B, and isogemichalcone C[J]. Tetrahedron, 2013, 69(47): 9994-10002.

  [2]. Kang Y J, et al. Inhibitory effects of morachalcone A on lipopolysaccharide-induced nitric oxide production in raw 264.7 cells[J]. 2009.

  [3]. Ferlinahayati, et al. Phenolic constituents from the wood of Morus australis with cytotoxic activity. Z Naturforsch C J Biosci. 2008 Jan-Feb;63(1-2):35-9.  [Content Brief]