mPEG-amine (MW 5000)  (Synonyms: mPEG-NH2 (MW 5000))

mPEG-amine (mPEG-NH2) (MW 5000) is a modifier that can replace the sulfonic acid portion of the dye molecule to increase the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes. mPEG-amine can also form amide bonds with carboxyl groups on the surface of microspheres under the mediation of EDC and Sulfo-NHS to form a PEG coating on the surface of fluorescent microspheres for large-scale rotational cytoplasmic flow studies^[1][2].

PROTAC 含有两个通过接头连接的不同配体；一个是 E3 泛素连接酶的配体，另一个是靶蛋白的配体。PROTAC 利用细胞内泛素-蛋白酶体系统选择性降解靶蛋白^[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PROTAC 含有两个通过接头连接的不同配体；一个是 E3 泛素连接酶的配体，另一个是靶蛋白的配体。PROTAC 利用细胞内泛素-蛋白酶体系统选择性降解靶蛋白^[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

5000(Average)

(C₂H₄O)_nC₃H₉NO

80506-64-5

固体

White to off-white

甲氧基聚乙二醇胺 (MW 5000)

Room temperature in continental US; may vary elsewhere.

• [1]. Patrick MJ, et al. Enhanced aqueous solubility of long wavelength voltage-sensitive dyes by covalent attachment of polyethylene glycol. Org Biomol Chem. 2007 Oct 21;5(20):3347-53.  [Content Brief]

  [2]. Suzuki K, et al. Spatial confinement of active microtubule networks induces large-scale rotational cytoplasmic flow. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):2922-2927.  [Content Brief]