1. Anti-infection
  2. Bacterial
  3. N-Decanoyl cyclopentylamide

N-Decanoyl cyclopentylamide  (Synonyms: C10-CPA)

目录号: HY-158193
产品使用指南

N-Decanoyl cyclopentylamide (C10-CPA) 是铜绿假单胞菌中群体感应的强效抑制剂。N-Decanoyl cyclopentylamide 会干扰由 lasrhl 群体感应系统调节的铜绿假单胞菌毒力因子的表达。N-Decanoyl cyclopentylamide 可抑制弹性蛋白酶、绿脓素和鼠李糖脂的产生以及生物膜的形成。

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N-Decanoyl cyclopentylamide Chemical Structure

N-Decanoyl cyclopentylamide Chemical Structure

CAS No. : 540796-75-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N-Decanoyl cyclopentylamide (C10-CPA) is a potent inhibitor of quorum sensing in Pseudomonas aeruginosa. N-Decanoyl cyclopentylamide interferes with expression of Pseudomonas aeruginosa virulence factors regulated by the las and rhl quorum-sensing systems. N-Decanoyl cyclopentylamide inhibits production of elastase, pyocyanin, and rhamnolipid and biofilm formation[1].

体外研究
(In Vitro)

N-Decanoyl cyclopentylamide (C10-CPA) 可抑制铜绿假单胞菌中的群体感应,其对 lasB-lacZ 和 rhlA-lacZ 表达的半数最大抑制所需的浓度分别为 80 μM 和 90 μM[1]
N-Decanoyl cyclopentylamide 还可抑制毒力因子的产生,包括弹性蛋白酶、绿脓素和鼠李糖脂,以及生物膜的形成,而不会影响铜绿假单胞菌 PAO1 的生长[1]
N-Decanoyl cyclopentylamide 通过抑制其反应调节剂 (LasR 和 RhlR) 与自诱导剂之间的相互作用来干扰 lasrhl 群体感应系统[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

239.40

Formula

C15H29NO

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

N-Decanoyl cyclopentylamide 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
N-Decanoyl cyclopentylamide
目录号:
HY-158193
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