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N-(p-Tosyl)-GPR-pNA acetate  (Synonyms: Chromozym-TH)

目录号: HY-138143
产品使用指南

N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) 是靶向合成肽 Hirunorm IV 和 Hirunorm V 的显色底物,可用于检测两种肽的解离常数 (KI)。Hirunorm IV 和 Hirunorm V 是酰胺分解凝血酶活性的可逆抑制剂。通过改变显色底物 N-(p-Tosyl)-GPR-pNA acetate 固定浓度下的肽浓度,测定的解离常数分别为 0.134 nM (Hirunorm IV) 和 0.245 nM (Hirunorm V)。

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N-(p-Tosyl)-GPR-pNA acetate Chemical Structure

N-(p-Tosyl)-GPR-pNA acetate Chemical Structure

CAS No. : 86890-95-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

N-(p-Tosyl)-GPR-pNA acetate (Chromozym-TH) is a chromogenic substrate targeting the synthetic peptides Hirunorm IV and Hirunorm V and can be used to detect the dissociation constants (KI) of both peptides. Hirunorm IV and Hirunorm V are reversible inhibitors of amidolytic thrombin activity. By varying the peptide concentration at a fixed concentration of the chromogenic substrate N-(p-Tosyl)-GPR-pNA acetate, the dissociation constants determined were 0.134 nM (Hirunorm IV) and 0.245 nM (Hirunorm V)[1].

IC50 & Target

Hirunorm IV, Hirunorm V[1]

分子量

662.71

Formula

C28H38N8O9S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

N-(p-Tosyl)-GPR-pNA acetate 相关分类

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
N-(p-Tosyl)-GPR-pNA acetate
目录号:
HY-138143
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