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  4. NEU3-IN-1

NEU3-IN-2 (compound 963) 是基于 2-脱氧-2,3-二脱氢-N-乙酰神经氨酰 (DANA) 支架的 NEU3 抑制剂 (Ki: 0.12 μM；IC50: 0.31 μM)，是 C9 联苯氨基甲酸酯衍生物。NEU 是人类神经氨酸酶，有 4 种同工酶；NEU3-IN-2 是研究 NEU3 同工酶功能的重要工具；其酰胺和三唑接头类似物分别对 NEU1 和 NEU4 同工酶具有选择性。

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NEU3-IN-1 Chemical Structure

NEU3-IN-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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NEU3-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NEU3-IN-2 (compound 963) is a NEU3 inhibitor (Ki: 0.12 μM; IC50: 0.31 μM) based on the 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) scaffold and is a C9 biphenylcarbamate derivative. NEU is a human neuraminidase with 4 isozymes; NEU3-IN-2 is an important tool for studying the function of NEU3 isozymes; its amide and triazole linker analogs are selective for NEU1 and NEU4 isozymes, respectively[1].

IC50 & Target

Ki: 0.12 μM (NEU3)
IC50: 0.31 μM (NEU3)[1]
分子量

486.47

Formula

C24H26N2O9
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NEU3-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NEU3-IN-1OthersNEUInhibitorInflammationAtherosclerosisDiabetes mellitusinhibitorinhibit

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产品名称：
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目录号：
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